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as they re needed, as illustrated in Figure A.1. Consider what happens in a ctitious restaurant when a patron orders a particular dish. First, the chef s assistant locates the appropriate recipe (a gene) from the library of cookbooks (the collection of chromosomes, also known as the genome), each of which contains thousands of recipes. To keep the original recipes in pristine condition, individual cookbooks (chromosomes) aren t allowed out of the library. Instead, a copy (the intermediary, RNA) is made. In the hands of the chef, the copy directs the intricate operations that result in a dish (protein), which is promptly delivered to the patron. Following this metaphor, a bad recipe (a genetic disease) can be recti ed by editing (modifying) either the original recipe (gene) in the appropriate book (chromosome) in the library (genome) or the copy (RNA). Modifying a gene is the basis of clinical therapeutics. New recipes (genes) can be inserted into books (chromosomes) in the library, which make new dishes (proteins) possible. Creating new proteins by inserting new genes into humans, plants, or livestock, is the basis of new

In most cases, properties are public The primary purpose of properties is to provide public access to the data relating to a particular object But in some cases, you may want the property to be read-only and, in rare cases, write-only You can de ne a property s accessibility using additional keywords in the Property statement

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(6.2.26) (6.2.27)

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(6.2.28) (6.2.29)

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Some elds should be changed only by code in the class, not by any code outside the class For example, a ProductID should not be changed by code outside the class, because the ID is the key property used to identify the product It should be set only when the product is created and then never changed (See 8 for more information on primary key elds) You can de ne a property to be read-only using the ReadOnly keyword If you need to de ne a property as write-only, you can use the WriteOnly keyword

E(r)

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to a process in which a single recipe (a gene composed of DNA) from a library of recipes (chromosomes) is copied, and this copy (the RNA) serves as the instructions for creating particular dishes (proteins).

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When you make the property read-only or write-only using the keyword, the code in the class cannot access the property either If the property is read-only, the code in the class must access the private backing variable to update the value It would be better to de ne the accessibility on the accessors so that the getter could be public but the setter could be private This would allow the code in the class to set the property but make it appear read-only outside this class To de ne separate accessibility on the accessors, add an accessibility keyword to either the getter or setter:

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(1",1"')

(1"')

(6.2.30)

Public Property ProductID() As Integer Get End Get Private Set(ByVal value As Integer) End Set End Property

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drug development. For example, genes for insulin can be inserted into bac teria so that they synthesize insulin, which is collected, puri ed, and sold as a therapeutic drug to patients with diabetes. Genes from different chromosomes can be combined in novel ways just as the recipe for a sauce from a dessert cookbook could be combined with the recipe of a pasta dish from a cookbook of entrees. The result would be a unique dish that may never have been seen before. This is akin to creating organisms that have genes from multiple species, such as pig genes combined with tomato genes to create a bruise-resistant tomato. In some cases, a particular recipe may have application outside of sat isfying a patron s hunger. For example, the starch from boiling potatoes can be used as a fabric stiffener in a laundry service, and the wax from a honeycomb can be melted and used to fabricate candles. What s more, the potatoes can be genetically modi ed so that they release much more starch when boiled. This is akin to creating biomaterials. Finally, some recipes can be modi ed to the point that they are poiso nous. A dish can be laced with warfarin rat poison for example, and used to rid the kitchen of a rodent problem. The parallel is creating biolog ical weapons against people, crops, and farm animals. Following are examples of the science of biotechnology in the context of their practical application.

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Notice the Private keyword on the setter This allows the getter to be public but restricts the setter to be private The code within the class can then get or set the property, and code outside the class can only get the property

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